Ketamine Infusion Therapy

ABout Ketamine Infusion

At Rune Vitality, ketamine infusion therapy is offered as part of a comprehensive approach to care for select patients experiencing difficult-to-treat mental health conditions and chronic pain. 

Ketamine infusion therapy is intended to complement — not replace — your existing mental health or pain management care.

Session length:

40 minutes to 4 hours, depending on diagnosis.

What is Ketamine Infusion Therapy?

Ketamine is an FDA-approved anesthetic that has been studied for its effects on depression, PTSD, anxiety and certain chronic pain conditions. Its use for these conditions is considered off-label.

Ketamine stimulates the production of healthy neurotransmitters and helps to re-establish nerve connections. If you’ve tried prescription medication and other forms of treatment and have not had the results you desire, ketamine infusion may be the right option for you.

Treatment is provided in a calm, professional environment with continuous monitoring. We offer ketamine by IV infusion only, which lets our clinical team control your dose precisely and adjust it throughout your session for a more comfortable, personalized experience.

Conditions We Treat

Treatment-Resistant Depression

For individuals who have not experienced adequate improvement with conventional treatments, infusion therapy may provide another option to discuss with their healthcare team. Each patient receives an individualized evaluation to determine whether treatment is appropriate.

Ketamine therapy may be considered as part of a comprehensive treatment approach for individuals with post-traumatic stress disorder. Treatment is individualized and coordinated with existing mental health care providers.

Individuals experiencing significant or persistent anxiety may be evaluated for this treatment option when appropriate. A thorough medical and mental health assessment helps determine whether therapy is suitable.

Chronic neuropathic pain conditions involving nerve-related pain may respond to infusion-based treatment. Therapy is individualized according to the patient’s diagnosis, symptoms, medic

People living with CRPS may experience persistent, difficult-to-manage neuropathic pain. Infusion therapy may be considered as one component of a comprehensive pain management strategy.

With fibromyalgia and chronic widespread pain, this therapy may be considered when conventional approaches have not provided sufficient relief.

The Results

Many patients report an improvement in mood and general well-being after the first few treatments. It is not uncommon for patients to feel relief within several hours of their first infusion.


The length of your results will vary for each individual and can last for several months. Following your initial series of treatments, we can work with you to begin a maintenance program.

Ketamine Infusion Clinic in San Marcos, CA

When depression, anxiety, PTSD or chronic pain haven’t improved with other treatments, it can feel like you’ve run out of options. Ketamine infusion therapy offers a different approach. Rune Vitality provides IV ketamine therapy in a calm, private infusion room in San Marcos, with practitioner-guided care from your first consultation through every session.

How IV Ketamine Works for Depression

Most antidepressants work on serotonin and can take weeks to have an effect. Ketamine works on a different system in the brain, glutamate, and is thought to help the brain form new connections. That’s why some patients notice changes in mood after only a few infusions. Ketamine has been studied extensively for treatment-resistant depression.

Why IV Ketamine Infusions

We offer ketamine only by IV infusion. With IV ketamine, the dose is precise and can be adjusted during your session, and you’re monitored by our clinical team throughout.

Ketamine Therapy for Depression and Anxiety, PTSD and Pain

Our ketamine treatment programs are designed for adults with treatment-resistant depression, anxiety, PTSD, and some chronic pain conditions such as neuropathic pain, CRPS and fibromyalgia. Ketamine is meant to work alongside your existing mental health care, not replace it.

Working With Your Mental Health Provider

We work with your current mental health provider to make sure ketamine infusion therapy is appropriate for you. That partnership continues throughout treatment, so your care stays coordinated.

What to Expect

Every ketamine patient starts with a conversation and a professional consultation. We review your history, current treatment and goals to confirm that ketamine infusion therapy is a safe and appropriate fit. Treatment is always in person at our San Marcos clinic, and you cannot drive home after a ketamine infusion.

We serve patients across San Diego County, including San Marcos and North County, and Riverside County, including Temecula.

Real People. Real Vitality. Real Impact

Posted on Google Google
Tammy Baxter profile picture
Tammy Baxter
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
The IV Therapy I had today was so relaxing. Robert shared with me many types of IV Therapy he handles. I will definitely be back! Next time I may try the NMN Supplement he told me all about. He was very informative! I highly recommend this business!!
Posted on Google Google
Eric Rogel profile picture
Eric Rogel
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
The experience was amazing and knowledgeable. . . . Rob took his time and explained everything and made sure he was there for our every need i really recommended they check this place out 10/10 experience i will definitely go back
Posted on Google Google
Shirin Alipanah profile picture
Shirin Alipanah
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Great location and super easy to get to! Very flexible with a busy schedule, great pricing, and such a welcoming, professional, and comfortable environment. Rob really take the time to answer your questions and make sure you’re fully informed before choosing an IV package. Highly recommend!
Posted on Google Google
Dagmar Pavel profile picture
Dagmar Pavel
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Robert was very professional and went above and beyond to accommodate my needs! I highly recommend this business for all your IV therapy needs!
Posted on Google Google
Tanya Vasquez profile picture
Tanya Vasquez
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
I am an extremely satisfied customer. Communication and service has been the absolute best.
Posted on Google Google
Eric Johnson profile picture
Eric Johnson
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
10 stars for Rob and the service provided. Great experience, will be recommending to others.
Posted on Google Google
Ruben Rodriguez profile picture
Ruben Rodriguez
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Amazing place and amazing people . Will keep going back for sure . Rob is an amazing provider.

Frequently Asked Questions

Got Questions? Reach out to our team directly. 

What is ketamine therapy used for?

Ketamine-assisted therapy is commonly used to support mental wellness, including mood, stress resilience, and emotional health.  Ketamine is used when conventional treatments have failed.  Common diagnoses include treatment-resistant depression, PTSD, anxiety, neuropathic pain, complex regional pain disorder, fibromyalgia.

Sessions take place in a calm, supportive environment with continuous monitoring. Most patients describe the experience as introspective and restorative.

During an infusion, people may feel dissociated or dreamy, and some have nausea, dizziness or a temporary rise in blood pressure. These effects usually fade soon after the infusion ends. You’re monitored throughout every session.

The average course of ketamine infusion therapy consists of six treatment sessions over the course of 3 weeks. However, depending on your condition and symptoms, you may need additional treatments.

All treatment plans are customized to the patient from the infusion schedule to dosage to ensure optimal results. 

No. You cannot drive home after a ketamine infusion. Plan to rest for the remainder of the day.

It starts with a conversation and a professional consultation. We review your diagnosis, current treatment and goals, and we work with your current mental health provider to make sure ketamine is appropriate for you.